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My research focuses on the functions of
prefrontal cortex and its connections to the rest of the
brain.
I try to characterize systems that support our ability to
flexibly modulate behavior and goals based on external
feedback as well as internal representations derived from
past experience. In that line, current projects include
using dynamic virtual reality paradigms and fMRI to explore
the contributions of different brain circuits during
planning and decision-making.
Connectivity ought to constrain our interpretation of
function. I use functional connectivity MRI methods to map
connections of human prefrontal cortex to the rest of the
cerebrum and the cerebellum.
Fenna's [website]
Krienen,
F.M., Tu, P.C.,
Buckner, R.L. (2010) Clan mentality: evidence that medial
prefrontal cortex responds to close others. J Neurosci; in
press.
Krienen,
F.M., Buckner, R.L.
(2009) Segregated fronto-cerebellar circuits revealed by
functional connectivity. Cereb Cortex;
19(10):2485-97. [medline abstract]
Buckner, R.L., Sepulcre, J., Talukdar, T.,
Krienen,
F.M., Liu, H.,
Hedden, T., Andrews-Hanna, J.R., Sperling, R.A., Johnson,
K.A. (2009) Cortical hubs revealed by intrinsic functional
connectivity: mapping, assessment of stability, and
relation to Alzheimer’s disease. J Neurosci;
29(6):1860-73. [medline abstract]