I am interested in the
cognitive neuroscience of normal and pathological human
aging. I especially like to use longitudinal behavioral
data and fMRI methods. More specifically, my project at
Harvard Psychology / Martino’s Center is aimed at
investigating links between age related changes in the
state of the brain when people are just thinking by
themselves and compensational mechanisms when the brain is
challenged with a complex task.
Van Dijk,
K.R.A., Sperling,
R.A. (2011) Defaulting on the default network: Increased
risk for dementia, Neurology; 76 (6): 498-500.
[full text]
Drzezga, A., Becker, A.J., Van Dijk, K.R.A., Sreenivasan, A., Talukdar, T.,
Sullivan, T., Schultz, A.P., Sepulcre, J., Putcha, D.,
Greve, D., Johnson, K.A., Sperling, R. (in press) Neuronal
dysfunction and disconnection of cortical hubs in
non-demented subjects with elevated amyloid-burden, Brain.
Van Dijk,
K.R.A, Hedden, T.,
Venkataraman, A., Evans, K.C., Lazar, S.W., Buckner, R.L.
(2010) Intrinsic functional connectivity as a tool for
human connectomics: theory, properties, and optimization,
Journal of Neurophysiology; 103: 297-321.
[full text]
Hedden, T., Van
Dijk, K.R.A.,
Becker, A.J., Mehta, A., Sperling, R.A., Johnson, K.A.,
Buckner, R.L. (2009) Disruption of functional connectivity
in clinically normal older adults harboring amyloid burden,
Journal of Neuroscience; 29 (40): 12686-12694.
[full text]
Van Dijk, K.R.A.,
Van Gerven, P.W.M., Van Boxtel, M.P.J., Van der Elst, W.,
Jolles, J. (2008) No protective effects of education during
normal cognitive aging: results from the 6-year follow-up
of the Maastricht Aging Study (MAAS), Psychology and Aging;
23 (1): 119-130. [full text]
Van Dijk,
K.R.A., Luijpen,
M.W., Van Someren, E.J.W., Sergeant, J.A., Scheltens, P.,
Scherder, E.J.A. (2006) Peripheral electricalnerve
stimulation in Alzheimer's disease: a randomized controlled
trial on the rest-activity rhythm, Journal of Sleep
Research; 15 (4): 415-423. [full text]
