Dr. Juttukonda’s research interests are in studying the balance between hemodynamic and metabolic function in the human brain as well as in the translation of these methods for characterizing microvascular health in cerebrovascular diseases. A principal objective of his work has been to develop q...
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Estimating Tumor Boundaries in Cancer Surgery With Fluorescence Lifetime Imaging
Cancer is the second leading cause of death in the United States, with an estimated 1,762,450 new cases diagnosed and 606,880 deaths in 2019 alone. While important advances have been made in the development of treatments for cancer, including surgery, a number of challenges remain. Not least: sur...
Matt Rosen and Colleagues’ Journey Through the Secret Life of Plants
In the waning months of 1979, the legendary Motown artist Stevie Wonder released an album called Stevie Wonder’s Journey Through "The Secret Life of Plants," the soundtrack to the documentary film The Secret Life of Plants. Equal parts frustrating and strangely compelling, and notably using some ...
Nanodiamond-enhanced MRI: A Dazzling New Approach to Imaging
Nanodiamonds – synthetic industrial diamonds only a few nanometers in size – have recently attracted considerable attention because of the potential they offer for the targeted delivery of vaccines and cancer drugs as well as for other uses. Thus far, options for imaging nanodiamonds have been li...
Jason Stockmann
Jason Stockmann, PhD, is broadly interested in magnetic resonance imaging hardware and acquisition methods for improving data quality for both structural and functional imaging. He has worked on diverse MRI scanners ranging in field strength by two orders of magnitude, from low-field (80 mT) to u...
White Matter Changes Could Predict Cognitive Decline in Alzheimer’s Disease
Alzheimer’s disease is diagnosed based on abnormal pathology of two proteins in the brain: amyloid and tau. Research suggests, however, that other factors may also play a role. In a paper published online this week in the journal Neurology, a team of investigators at the Athinoula A. Martinos Cen...
Understanding Eye-contact Avoidance in People With Autism
Individuals with autism spectrum disorder (ASD) often have difficulty looking others in the eyes. This is typically interpreted as a sign of social and personal indifference, but self-reports from people with autism suggests otherwise. Many say that looking others in the eye is uncomfortable or s...
Visualizing the Mind: How We See the Brain Through Functional MRI
Last year, Harvard College senior Kelsey Ichikawa (shown in the photo above) interviewed the Martinos Center’s Bruce Rosen and Bruce Fischl for a general audience article about functional MRI, which she was writing for a science journalism course. Earlier this year, the article won the Harvard Bo...
New Software Concept Promises Boost for Clinical Trial Recruitment
What if you held a clinical trial and nobody came? While plenty of patients are eager to participate, researchers often have difficulty reaching their target enrollments for clinical trials, the goal of which is to determine the safety and efficacy of new drugs or therapies before they are bro...
The Epigenetics of Aging: Understanding neurodegeneration at the gene transcription level
Over the past century, life expectancy has doubled. Consider for a moment the impact of this factoid on our interpretation of the aging brain. Prior to the 20thcentury – indeed, throughout nearly all of history – there was likely no evolutionary pressure for humans to live beyond reproductive age...
Deep Learning Algorithm Can Measure Disease Severity and Change on a Continuous Spectrum
Clinicians often use imaging to evaluate both the severity and progression of disease, in many cases by assigning severity to one of several categories based on the imaging findings and seeing whether and how the classification changes on follow-up. This approach can have its limits, though. B...
20 Years of FreeSurfer
It’s a sunny day in Southern California and the developers of FreeSurfer—a suite of software tools for the analysis of neuroimaging data—are preparing for a training session to introduce scientists to the many benefits of the package. To help the scientists find the classroom they have hung “Free...
Acupuncture Yields Improved Outcomes in Carpal Tunnel Syndrome
Though the practice of acupuncture predates current understanding of physiology by several millennia, it often provides measureable improvements in health outcomes, particularly in the area of chronic pain. Now, in a study reported in the journal Brain, a team of investigators based at the Athino...
The Secret Lives of Martinos Folk: It’s Gonna Be a Lot Less Spooky Around Here
If you were in Building 149 of the Martinos Center on any given Halloween in the past decade, you might have come across a possibly startling scene: a nine-foot, anthropomorphic volcano wandering the halls; a moth-man with large, glowing eyes posing for photos; or maybe just a huge globule of glu...
Facilitating Integration of AI Into Radiology Practice
The Quantitative Translational Imaging in Medicine (QTIM) Lab at the MGH Martinos Center has contributed to the advancement of artificial intelligence in radiology practice in myriad ways. Not least: the group collaborated with the American College of Radiology Data Science Institute (ACR-DSI) in...
Andre van der Kouwe
Dr. van der Kouwe does research in the field of MRI pulse sequence design and image analysis. He supports neuroscience research at the MGH and collaborating institutions by improving acquisition methods, providing techniques such as high-reliability imaging for quantitative brain morphometry with...
Thomas Deisboeck
Tom Deisboeck has spent over 25 years in life sciences research. He holds an MD (Dr. med) from the Technical University of Munich as well as an MBA from Massachusetts Institute of Technology (MIT). Dr. Deisboeck is an Associate Professor of Radiology (PT) at Massachusetts General Hospital and Har...
From the “We Already Knew This” File: Partners Recognizes Donna Crowe’s Excellence
The Center’s Donna Crowe received a “Partners in Excellence” award for her always outstanding work as office manager and executive assistant to the director of the MGH Martinos Center for Biomedical Imaging. She accepted the award at a ceremony held last month. In addition to her many duties a...
It’s Never Too Early to Learn About MRI
Here in the Martinos Center, our education mission extends all the way to teaching children enrolled in the preschool down the street in the Charlestown Navy Yard. Once a year, the Center’s Allison Stevens welcomes a group of the children, explains to them what MRI is and what it does, and str...