Karl Helmer
Assistant Professor of Radiology
Email: KHELMER@mgh.harvard.edu
Recent Publications
- Yu H, Lee H, Lee M, Kim D, Pirpamer L, Duering M, Moy S, Helmer KG, Kim REY. Multi-center evaluation of Neurophet AQUA for brain MRI segmentation: T1 compared with FreeSurfer and T2-FLAIR compared with ground truth. Front Neurol. 2025. 16:1672133
- Gesierich B, Pirpamer L, Meier DS, Amann M, Cerfontaine MN, de Leeuw FE, Maillard P, Moy S, Helmer KG, Kühne M, Bonati LH, Rutten JW, Lesnik Oberstein SAJ, Duering M. Technical and clinical validation of a novel deep learning-based white matter hyperintensity segmentation tool. Cereb Circ Cogn Behav. 2025. 9:100393
- García-Cazorla Á, Sevin C, Constante JR, Yazbeck E, Rosewich H, Jimenez S, Chia-Yi Chiang G, Rapalino O, Caruso P, Balentine D, Helmer KG, Bennett S, Emanuele M, Rodriguez-Pascau L, Pizcueta P, Pina G, Vilà A, Rovira M, Mantilla A, Meya U, Mistry A, Pascual M, Pascual S, Martinell M, Musolino PL, Mallack E. Safety and efficacy of leriglitazone in childhood cerebral adrenoleukodystrophy (NEXUS): an interim analysis of an open-label, phase 2/3 trial. EClinicalMedicine. 2025 Jun. 84:103265
- Gesierich B, Sander L, Pirpamer L, Meier DS, Ruberte E, Amann M, Sinnecker T, Huck A, de Leeuw FE, Maillard P, Moy S, Helmer KG, Levin J, Höglinger GU, Kühne M, Bonati LH, Kuhle J, Cattin P, Granziera C, Schlaeger R, Duering M. Extended Technical and Clinical Validation of Deep Learning-Based Brainstem Segmentation for Application in Neurodegenerative Diseases. Hum Brain Mapp. 2025 Feb 15. 46(3):e70141
- Liu X, Maillard P, Barisano G, Caprihan A, Cen S, Shao X, Jann K, Ringman JM, Lu H, Arfanakis K, DeCarli CS, Gold BT, Seshadri S, Satizabal CL, Beiser AS, Habes M, Kramer JH, Stables L, Singh H, Helmer KG, Greenberg SM, Wang DJJ. MRI free water mediates the association between diffusion tensor image analysis along the perivascular space and executive function in four independent middle to aged cohorts. Alzheimers Dement. 2025 Feb. 21(2):e14453
