Instructor in Radiology

Email: jwdowney@mgh.harvard.edu

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Recent Publications

• Cheng H, Narayan NS, Wang Y, Wang Y, Huang Y, Yang H, Tokala R, Yan J, Downey JW, Siewko A, Varela BL, Hallisey MR, Geronimo TA, Banick MM, Tanzi RE, Zhang C, Xu Y, Wang C. Neuroimaging of indoleamine 2,3-dioxygenase 1 (Ido1) in Alzheimer's disease: Development of a novel 18F-labeled PET tracer. Mater Today Bio. 2026 Dec. 41:103682
• Gallagher E, Downey JW, Yoo CH, Deng H, Fu JF, Qin Q, Bass I, Wey HY, Hooker JM, Sander CY, Lee SJ. Quantitative µ-Opioid Receptor PET with [18F]FCFN in Nonhuman Primates: Naloxone Blockade and Within-Scan Displacement. Pharmaceutics. 2026 Sep 10. 18(9)
• Bagdasarian FA, Guma E, Tokala R, Yoo CH, Downey JW, Hooker JM, Zürcher NR, Wey HY. [18F]AzaFol PET captures folic acid dynamics at folate receptors in the brain. J Cereb Blood Flow Metab. 2026 Apr. 46(4):976-986
• Tokala R, Yoo CH, Downey JW, Varela BL, Wey HY, Lee SJ, Hooker JM. Quantitative Imaging of ATM: PET and Autoradiography Studies Using [11C]AZD1390. ACS Chem Neurosci. 2025 Oct 15. 16(20):4101-4110