Karl Helmer
Assistant Professor of Radiology
Email: KHELMER@mgh.harvard.edu
Recent Publications
- Yu H, Lee H, Lee M, Kim D, Pirpamer L, Duering M, Moy S, Helmer KG, Kim REY. Multi-center evaluation of Neurophet AQUA for brain MRI segmentation: T1 compared with FreeSurfer and T2-FLAIR compared with ground truth. Front Neurol. 2025. 16:1672133
- Greenberg SM, Albert MS, An H, Arfanakis K, Evia AM, Caprihan A, Ford AL, Fornage M, Day GS, Hinman JD, Jicha GA, Kashani AH, Kramer JH, Lachner C, Lee JM, Liu P, Lu H, Maillard P, Petersen RC, Psaty BM, Ringman JM, Rosenberg GA, Satizabal CL, Savitz SI, Schneider JA, Seshadri S, Vemuri P, Wang DJJ, Wilcock DM, Windham BG, Zhang R, Tuozzo C, Singh H, Moy S, Okey-Ewurum V, Page CB, Mulder H, Kivisäkk P, Blacker D, Mazina L, Helmer KG, Schwab K, Wruck LM, Corriveau RA. MarkVCID2 Consortium for Clinical Validation of Biomarkers of Cerebral Small Vessel Disease: Validation Framework and Baseline Characteristics. Ann Neurol. 2026 02. 99(2):449-458
- Gesierich B, Pirpamer L, Meier DS, Amann M, Cerfontaine MN, de Leeuw FE, Maillard P, Moy S, Helmer KG, Kühne M, Bonati LH, Rutten JW, Lesnik Oberstein SAJ, Duering M. Technical and clinical validation of a novel deep learning-based white matter hyperintensity segmentation tool. Cereb Circ Cogn Behav. 2025. 9:100393
- García-Cazorla Á, Sevin C, Constante JR, Yazbeck E, Rosewich H, Jimenez S, Chia-Yi Chiang G, Rapalino O, Caruso P, Balentine D, Helmer KG, Bennett S, Emanuele M, Rodriguez-Pascau L, Pizcueta P, Pina G, Vilà A, Rovira M, Mantilla A, Meya U, Mistry A, Pascual M, Pascual S, Martinell M, Musolino PL, Mallack E. Safety and efficacy of leriglitazone in childhood cerebral adrenoleukodystrophy (NEXUS): an interim analysis of an open-label, phase 2/3 trial. EClinicalMedicine. 2025 Jun. 84:103265
- Gesierich B, Sander L, Pirpamer L, Meier DS, Ruberte E, Amann M, Sinnecker T, Huck A, de Leeuw FE, Maillard P, Moy S, Helmer KG, Levin J, Höglinger GU, Kühne M, Bonati LH, Kuhle J, Cattin P, Granziera C, Schlaeger R, Duering M. Extended Technical and Clinical Validation of Deep Learning-Based Brainstem Segmentation for Application in Neurodegenerative Diseases. Hum Brain Mapp. 2025 Feb 15. 46(3):e70141