Professor of Psychiatry

Email: dholt@partners.org

---

Recent Publications

• Levitt JJ, Zhang F, Vangel M, Nestor PG, Rathi Y, Cetin-Karayumak S, Kubicki M, Pasternak O, Coleman MJ, Lewandowski KE, Holt DJ, Keshavan M, Bouix S, Öngür D, Breier A, Shenton ME, O'Donnell LJ. Diagnostic and sex effects on frontostriatal brain wiring structural organization in early psychosis affective subjects compared to healthy controls. Mol Psychiatry. 2026 Jul 04.
• McKenna F, Vinke LN, Williams M, Gaw M, Dunk M, Jacobs H, Cohen L, Holt DJ. Postpartum psychosis is associated with elevated neuromelanin-MRI signal in the midbrain. Mol Psychiatry. 2026 Jun. 31(6):3524-3532
• Clauss JA, Babadi B, Tuominen L, Deng W, Leathem L, Holt DJ. Neurobehavioral Changes in Fear Generalization in Clinical High Risk for Psychosis. medRxiv. 2026 Jan 16.
• Clauss JA, Foo CYS, Leonard CJ, Dokholyan KN, Cather C, Holt DJ. Screening for Psychotic Experiences and Psychotic Disorders in General Mental Health Treatment Settings: A Systematic Review and Meta-Analysis. Harv Rev Psychiatry. 2026 Jan 01. 34(1):23-43
• McKenna F, Vinke LN, de Marneffe F, Avananki M, Holt DJ. Association between loneliness and hippocampal responses to dynamic social stimuli in psychotic disorders. Psychol Med. 2025 12 29. 55:e388