The Center's magnetic resonance imaging (MRI) facilities include the following. Large-bore MRI Systems * All subject bays are equipped with Blu-ray/DVD players for subject entertainment Bay 1: Siemens 3T MRI Skyra with 128ch receive capabilities and 2ch pTx This is a Siemens 3T Skyra wit...
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Julie Price
One of the Center's newest senior faculty members, Julie Price, PhD, brings to the Martinos community a wealth of experience with quantitative positron emission tomography (PET). With this technique, researchers study the dynamics of the PET radiotracer in vivo in order to obtain absolute measure...
Jyrki Ahveninen
Dr. Ahveninen's mission is to apply novel and improved techniques to achieve more accurate estimates of human brain function than previously achieved. His work focuses on neuroimaging of human auditory system, auditory working memory and higher-order auditory cognition using techniques including ...
Early Screening of ASD With a New Eye-tracking Paradigm
Studies have shown that early diagnosis and intervention significantly impact the prognosis of individuals with autism spectrum disorder (ASD): the earlier the detection and diagnosis, the better the prognosis and functional status later in life. Currently, the average age of diagnosis is approxi...
Shahin Nasr
For the past 15 years, Shahin Nasr, PhD, has studied the visual system of humans and non-human primates using a variety of techniques, from psychophysics and event-related potentials (ERP) to conventional and high-resolution functional MRI, in order to understand the neural mechanisms underlying ...
Ultrahigh-field MRI Tracks Development of Cortical Lesions in Multiple Sclerosis Patients
The development of lesions in the brain’s cortical gray matter is a strong predictor of neurological disability for people with multiple sclerosis (MS), according to a study reported today in the journal Radiology. The findings suggest a role for ultrahigh-field MRI in monitoring the progression ...
Roberta Sclocco
Dr. Sclocco has a background in bioengineering and signal processing, with specific training in non-invasive neuroimaging (e.g., fMRI, EEG) and peripheral autonomic data analyses. Since the beginning of her career, she have been interested in the interactions between the central and peripheral au...
5 Things You Didn’t Know About David Cohen and MEG
Last week the MGH Martinos Center dedicated its advanced magnetoencephalography (MEG) facility as the David Cohen MEG Laboratory. Cohen—the inventor of MEG, a leader in the field of biomagnetism for more than 50 years, and a Martinos Center faculty member who was instrumental in building and deve...
Magnetoencephalography Aids Diagnosis and Treatment of Epilepsy, Other Disorders
Originally used only for research purposes, magnetoencephalography (MEG) has been introduced into clinical care in recent decades. With applications in epilepsy already benefiting from its use, and still others on the horizon, the technique is helping to advance diagnosis and treatment for a rang...
Berkin Bilgic
MRI has demonstrated ability to provide exquisite contrast for non-invasive imaging. What limits its efficiency and sensitivity are the tradeoffs between scan time, resolution and signal-to-noise ratio. Dr. Bilgic's research is devoted to breaking this stalemate by developing new acquisition and ...
White Matter Changes Could Predict Cognitive Decline in Alzheimer’s Disease
Alzheimer’s disease is diagnosed based on abnormal pathology of two proteins in the brain: amyloid and tau. Research suggests, however, that other factors may also play a role. In a paper published online this week in the journal Neurology, a team of investigators at the Athinoula A. Martinos Cen...
With New PET Probe, Researchers Image Fibrosis of the Lungs
The MGH Martinos Center's Pauline Désogère and colleagues have described a new positron emission tomography (PET) probe that can help to advance noninvasive diagnosis of pulmonary fibrosis. Reported in a Science Translational Medicine paper published online today, the probe enables detection and ...
Nanodiamond-enhanced MRI: A Dazzling New Approach to Imaging
Nanodiamonds – synthetic industrial diamonds only a few nanometers in size – have recently attracted considerable attention because of the potential they offer for the targeted delivery of vaccines and cancer drugs as well as for other uses. Thus far, options for imaging nanodiamonds have been li...
Jason Stockmann
Jason Stockmann, PhD, is broadly interested in magnetic resonance imaging hardware and acquisition methods for improving data quality for both structural and functional imaging. He has worked on diverse MRI scanners ranging in field strength by two orders of magnitude, from low-field (80 mT) to u...
A New Role for Diffusion MRI in Treating Anxiety and Depression
Anxiety disorders and depression are widespread among adolescents in the U.S., affecting as many as one in four 13 to 18 year olds. Determining the best course of treatment can be difficult, though, as we still don’t fully understand the biology underlying them. Now, using cutting-edge brain i...
Deep Learning Offers Quantitative Means of Monitoring Disease Progression in Retinopathy of Prematurity
Retinopathy of prematurity (ROP) is an eye disorder affecting roughly two-thirds of premature infants weighing less than 250 g at birth and one of the leading causes of childhood blindness worldwide. Historically, clinical diagnosis of ROP has been subjective, resulting in considerable variabilit...
Ken Kwong and the Introduction of Noninvasive fMRI
In the early months of 1992 the neuroscience community was flush with excitement. Jack Belliveau, a graduate student with the MGH-NMR Center (now the MGH Martinos Center for Biomedical Imaging), had recently published in Science his pioneering work with functional MRI, and the possibilities of th...
Understanding Eye-contact Avoidance in People With Autism
Individuals with autism spectrum disorder (ASD) often have difficulty looking others in the eyes. This is typically interpreted as a sign of social and personal indifference, but self-reports from people with autism suggests otherwise. Many say that looking others in the eye is uncomfortable or s...
Estimating Tumor Boundaries in Cancer Surgery With Fluorescence Lifetime Imaging
Cancer is the second leading cause of death in the United States, with an estimated 1,762,450 new cases diagnosed and 606,880 deaths in 2019 alone. While important advances have been made in the development of treatments for cancer, including surgery, a number of challenges remain. Not least: sur...
Robert Savoy
Dr. Savoy received his academic training in applied mathematics at MIT (BS 1971; MS 1975) and experimental psychology at Harvard University (PhD 1980). This period included 10 years of work at Polaroid Corporation’s Vision Research Laboratory, after which he joined the newly formed Rowland Instit...