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New Molecular Imaging Tool Detects Pulmonary Fibrosis
‘It’s All in the Eyes’: The role of the amygdala in the experience and perception of fear
Researchers have long believed that the amygdala, an almond-shaped structure in the brain, is central to the experience and perception of fear. Studies initiated in the 1990s of a patient with a rare condition affecting the amygdala initially seemed to support this conclusion. However, as the MGH...
Functional MRI Marker Can Diagnose Migraine without Aura
The Possible Role of Glow Sticks—Yes, Glow Sticks—in Treating Alzheimer’s
A new imaging probe that could help to advance therapies for Alzheimer’s disease draws its inspiration from an unlikely source. Research suggests that Alzheimer’s is closely associated with increased levels of ‘reactive oxygen species’ (ROS) in the brain, but actual, in vivo evidence of this h...
Novel Evaluation of Cerebrovascular Response in Chronic Mild TBI
Understanding Eye-contact Avoidance in People With Autism
Individuals with autism spectrum disorder (ASD) often have difficulty looking others in the eyes. This is typically interpreted as a sign of social and personal indifference, but self-reports from people with autism suggests otherwise. Many say that looking others in the eye is uncomfortable or s...
With New PET Probe, Researchers Image Fibrosis of the Lungs
The MGH Martinos Center's Pauline Désogère and colleagues have described a new positron emission tomography (PET) probe that can help to advance noninvasive diagnosis of pulmonary fibrosis. Reported in a Science Translational Medicine paper published online today, the probe enables detection and ...
New Software Improves Ability to Determine the Cause of Stroke
Determining the cause of an ischemic stroke is critical to preventing a second one and is a primary focus in the evaluation of stroke patients. But for all the importance of identifying the cause, physicians have long lacked a robust and objective means to do so. Now a team of investigators at...
A New Link between Pain Widespreadness and Catastrophizing Thoughts about Pain
How iPads and Other Tablet Devices Could Improve Communication Skills in People With Autism
In recent years researchers have gained an increased understanding of the relationship between motor skills and the development of language, particularly in autism spectrum disorder (ASD). Given the core deficit in verbal communication in children and adults on the spectrum, the improved understa...
Human Whole-Brain Diffusion MRI Dataset Available Online
Reported by Fuyixue Wang and colleagues, it is the first publicly available reference dataset acquired in vivo at submillimeter resolution.
Noninvasive Imaging Strategy Detects Dangerous Blood Clots in the Body
Study Confirms Role of Structural Connectivity in Spread of Alzheimer’s Disease Pathology
In Alzheimer’s, the proteins amyloid-beta and tau begin to accumulate in the brain many years before any clinical signs of the disease are evident. Propagation of these proteins throughout the brain has been linked to cognitive decline in Alzheimer’s, but exactly how they spread has long been a m...
Metabolomic Information Highly Useful for Predicting Future Prostate Cancer
Optical Imaging Method Can Determine Cannabis Intoxication, According to New Study
Smart Chemiluminescence Probe Facilitates Optical Imaging of Amyloid-Beta
Developed by Chongzhao Ran and colleagues, the probe greatly improves the ability to detect amyloid-beta in vitro and in a mouse model of Alzheimer's disease.
Ultrahigh-field MRI Tracks Development of Cortical Lesions in Multiple Sclerosis Patients
The development of lesions in the brain’s cortical gray matter is a strong predictor of neurological disability for people with multiple sclerosis (MS), according to a study reported today in the journal Radiology. The findings suggest a role for ultrahigh-field MRI in monitoring the progression ...
MEG Method May Hold the Secret to Baldness
A variety of factors can stop hair from forming and growing properly, leading to hair diseases and baldness. A new method developed recently by investigators at the MGH Martinos Center for Biomedical Imaging examines the activity of hair follicles and could be useful for testing the effects of di...
Acupuncture Yields Improved Outcomes in Carpal Tunnel Syndrome
Though the practice of acupuncture predates current understanding of physiology by several millennia, it often provides measureable improvements in health outcomes, particularly in the area of chronic pain. Now, in a study reported in the journal Brain, a team of investigators based at the Athino...