Dr. Eva-Maria Ratai has been Director of Clinical Magnetic Resonance Spectroscopy at Massachusetts General Hospital (MGH) since 2003. After completing her doctoral thesis in physical chemistry at the University of Münster in Germany in 2000, and her first post-doctoral position in the Department of Chemistry at UC Davis, she accepted a postdoctoral fellowship with the Department of Radiology at MGH in 2002. After completing her fellowship, she joined the faculty of Harvard Medical School (HMS) in 2004 and is currently an associate professor of radiology at HMS. As Director of Clinical Spectroscopy, her clinical activities at MGH include the development, implementation and optimization of new MRI and MR spectroscopy pulse sequences and protocols, as well as data processing tools to improve patient diagnosis, guide therapy, and enhance clinical throughput. In addition to her clinical duties, Dr. Ratai has been conducting clinical research related to neoplasm and neuropathic pain as well as neurodegenerative diseases and neuro-developmental disorders including amyotrophic lateral sclerosis and spinocerebellar ataxia.


PhD in Physical Chemistry, University of Münster

Select Publications

1. Ratai EM, Alshikho MJ, Zürcher NR, Loggia ML, Cebulla CL, Cernasov P, Reynolds B, Fish J, Seth R, Babu S, Paganoni S, Hooker JM, Atassi N. Integrated imaging of [(11)C]-PBR28 PET, MR diffusion and magnetic resonance spectroscopy (1)H-MRS in amyotrophic lateral sclerosis. Neuroimage Clin. 2018 Aug 9;20:357-364.

2. Ratai EM, Zhang Z, Fink J, Muzi M, Hanna L, Greco E, Richards T, Kim D, Andronesi OC, Mintz A, Kostakoglu L, Prah M, Ellingson B, Schmainda K, Sorensen G, Barboriak D, Mankoff D, Gerstner ER; ACRIN 6684 trial group. ACRIN 6684: Multicenter, phase II assessment of tumor hypoxia in newly diagnosed glioblastoma using magnetic resonance spectroscopy. PLoS One. 2018 Jun 14;13(6):e0198548.

3. González RG, Fell R, He J, Campbell J, Burdo TH, Autissier P, Annamalai L, Taheri F, Parker T, Lifson JD, Halpern EF, Vangel M, Masliah E, Westmoreland SV, Williams KC, Ratai EM. Temporal/compartmental changes in viral RNA and neuronal injury in a primate model of NeuroAIDS. PLoS One. 2018 May 11;13(5):e0196949.


Director of Clinical MR Spectroscopy Massachusetts General Hospital

Charter member of the NIH Imaging Technology Development [ITD] study section

Partners in Excellence Award


Ratai Lab
The Quantitative Translational Imaging in Medicine Lab