Randy Gollub, MD, PhD, is Professor of Psychiatry at Harvard Medical School and Clinical Professor of Psychiatry with a secondary appointment in Radiology at Massachusetts General Hospital, where she serves as the Associate Director of Translational Research in the Neuroimaging Research Program. She has been on faculty at HMS/MGH since 1993.
The focus of Dr. Gollub’s research is at the interface between the technological advancement of neuroimaging acquisition and analysis methods and their application to basic and clinical neuroscience. One of the first investigators to use fMRI to study healthy and disordered human brains, she has contributed to the development and dissemination of best practices for using those technologies through publication of exemplar research studies conducted with collaborators in multiple domains. Studies originating in her lab have used multimodal magnetic resonance neuroimaging acquisitions, including BOLD fMRI, ASL, diffusion and structural scans, to investigate pain and modulation of pain by placebo and integrative medical treatments in healthy subjects and in patients suffering from chronic pain disorders.
Dr. Gollub also has an active research program in the domain of neuroimaging informatics that focuses on the within- and cross-site calibration and validation of neuroimaging data vital to the development of viable biomarkers as well as on technical and logistical efforts to aggregate large datasets for research. She has made multiple contributions including as site PI for a publicly available multi-site clinical imaging investigation of schizophrenia and as a co-developer of the Medical Imaging Informatics Bench to Bedside (mi2b2) workbench that enables images acquired during the conduct of clinical care to be used for secondary research purposes. This unique resource for accessing clinical images is integrated directly into the Research Patient Data Registry (RPDR) at Partners Healthcare institutions. She currently has several projects underway using mi2b2 acquired images for the study of MRI metrics of healthy brain development and detection of neonatal brain damage.
MD (MSTP), Duke University School of Medicine
PhD in Pharmacology, Duke University
1. Kong J, White N, Kwong K, Vangel M, Rosman IS, Gracely RH, et al. Using fMRI to dissociate sensory encoding from cognitive evaluation of heat pain intensity. Human Brain Mapping. 2006;27:715-21.
2. Gollub RL, Shoemaker JM, King MD, White T, Ehrlich S, Sponheim SR, et al. The MCIC collection: a shared repository of multi-modal, multi-site brain image data from a clinical investigation of schizophrenia. Neuroinformatics. 2013;11(3):367-88.
3. Ou Y, Zöllei L, Retzepi K, Castro V, Bates SV, Pieper S, et al. Using clinically-acquired MRI to construct age-specific ADC atlases: quantifying spatiotemporal ADC changes from birth to 6-year old. Human Brain Mapping. 2017;88(20):1912-8.
Dr. Gollub has a long-standing commitment to biomedical education. A member of the affiliate faculty of the Harvard Massachusetts Institute of Technology division of Health Sciences Technology (HST), she serves as Co-Training Director of the HST Neuroimaging Training Program and was the originating Course Director for HST.583 fMRI Data Acquisition and Analysis.