The MGH Martinos Center's Pauline Désogère and colleagues have described a new positron emission tomography (PET) probe that can help to advance noninvasive diagnosis of pulmonary fibrosis. Reported in a Science Translational Medicine paper published online today, the probe enables detection and ...
Search Results: Probe Development
Smart Chemiluminescence Probe Facilitates Optical Imaging of Amyloid-Beta
Developed by Chongzhao Ran and colleagues, the probe greatly improves the ability to detect amyloid-beta in vitro and in a mouse model of Alzheimer's disease.
The Possible Role of Glow Sticks—Yes, Glow Sticks—in Treating Alzheimer’s
A new imaging probe that could help to advance therapies for Alzheimer’s disease draws its inspiration from an unlikely source. Research suggests that Alzheimer’s is closely associated with increased levels of ‘reactive oxygen species’ (ROS) in the brain, but actual, in vivo evidence of this h...
The Past, Present and Future of Molecular Imaging @ Martinos
Over the past several months, the MGH Martinos Center has been both celebrating the past and looking toward the future of its molecular imaging effort – with a symposium held last fall and now a series of initiatives designed to bolster the molecular imaging community. While there has always b...
Changning Wang
Changning Wang, PhD, has a unique and broad background in molecular imaging, medicinal chemistry, pharmaceutical sciences and neuroscience. After finishing his doctoral studies, he joined Martinos Center for Biomedical Imaging as a research fellow and later as a trainee in the Harvard/MGH Nuclear...
Chongzhao Ran
Chongzhao Ran, PhD, is an Associate Professor in Radiology at Massachusetts General Hospital and Harvard Medical School. He received a Master's degree in medicinal chemistry from China Pharmaceutical University and a PhD in medicinal chemistry from Shanghai Institute of Pharmaceutical Industry, C...
MGH Launches the Center for Precision Imaging
Massachusetts General Hospital has announced the Center for Precision Imaging (CPI), associated with the Martinos Center for Biomedical Imaging and led by Martinos Center investigator Umar Mahmood. Precision medicine is a burgeoning field in which health outcomes are optimized by specifically tai...
Stefan Carp
Dr. Carp's research group focuses on the development and clinical translation of light-based non-invasive sensing and imaging methods for disease detection and management. Major thrusts include the use of near-infrared spectroscopy and tomography as well as diffuse correlation spectroscopy to adv...
Magnetic Resonance Imaging
The Center's magnetic resonance imaging (MRI) facilities include the following. Large-bore MRI Systems * All subject bays are equipped with Blu-ray/DVD players for subject entertainment Bay 1: Siemens 3T MRI Skyra with 128ch receive capabilities and 2ch pTx This is a Siemens 3T Skyra wit...
Ross Mair
As the Head of MR Physics at the Harvard University Center for Brain Science, Neuroimaging facility, Dr. Mair's role involves investigation and implementation of novel MRI methods for neuroimaging using the 3.0T MRI scanner, along with facility management duties. His research time has been split ...
Nutrition and Brain Growth in the Developing World
The aging pickup truck bounces along a dirt road somewhere outside Bissora, one of the larger towns in the Oio region of the West African nation of Guinea-Bissau. The road, a major thoroughfare in the region, is pocked with holes. The rest of the year these would be deep and dusty. But it’s July ...
Maria Angela Franceschini
Maria Angela Franceschini, PhD, is widely recognized as a leader in the field of diffuse optical imaging in both neuroscience and clinical neuro-monitoring applications. Her research interests lie mainly in the development of novel optical imaging methods to achieve a deeper understanding of the ...
Peter Caravan
Peter Caravan, PhD, is co-director of the Institute for Innovation in Imaging (I3) at Massachusetts General Hospital and a Professor of Radiology at Harvard Medical School. He leads a multidisciplinary and translational molecular imaging lab (the Caravan Lab) focused on the invention of novel mol...
Matthew Rosen
Dr. Matt Rosen is a physicist, tool-builder and inventor whose research bridges the spectrum from fundamental physics to applied bioimaging work in the field of MRI. He established the Low-Field MRI and Hyperpolarized Media Laboratory at the Athinoula A. Martinos Center for Biomedical Imaging to ...
The Center’s Yingying Ning Recognized for Her Work on Imaging Tissue Fibrogenesis
Yingying Ning, a postdoctoral fellow in the Caravan Lab at the Martinos Center for Biomedical Imaging, received the Young Investigator Award at the World Molecular Imaging Congress (WMIC) last month. The award recognizes Dr. Ning’s robust work in developing molecular magnetic resonance (MR) pr...
Yi-Fen Yen
Over the past two decades, Dr. Yen has devoted herself to the development of advanced MRI techniques, for hyperpolarized metabolic imaging, cancer imaging and functional imaging in clinical and pre-clinical research. She is an MR physicist with >100 publications in peer-reviewed scientific jou...
Christian Farrar
The Farrar group's research program is focused on the development of novel Magnetic Resonance molecular imaging contrast agents and methods and on the development of innovative Magnetic Resonance Imaging (MRI) methods for characterizing vascular structure and function. The tools being developed i...
Bin Deng
Bin Deng, PhD, is a biomedical scientist whose research interests revolve around near-infrared (NIR) spectroscopy, functional optical imaging, the interactions between NIR light and tissue, noninvasive optical biomarkers and the pathophysiology of diseases. Dr. Deng investigates the intersection ...
Iris Yuwen Zhou
Dr. Iris Yuwen Zhou is an Assistant Professor of Radiology at Massachusetts General Hospital and Harvard Medical School and a faculty member in the Athinoula A. Martinos Center for Biomedical Imaging. She has a background in both electronic engineering and biomedical engineering, with specific tr...
David Salat
The overarching aim of Dr. Salat's work is to understand mechanisms of neural disease and to implement novel approaches to reduce the impact of disease on the brain, cognition and clinical status. Clinically, there are two main clinical foci to his research. At the MGH Martinos Center, he directs...