Dr. Wang’s research focuses on developing new acquisition and reconstruction techniques to improve the imaging efficiency of MRI, and applying these technologies to different brain imaging applications, such as quantitative, functional and diffusion imaging, with the goal of achieving high sensitivity and specificity for mapping important brain functions and structures. Dr. Wang received her PhD degree from Harvard-MIT Health Sciences and Technology program with interdisciplinary training in electrical engineering, neuroscience and clinical sciences (pre-clinical curriculum at Harvard Medical School).
Dr. Wang has recently developed a novel acquisition method, termed Echo Planar Time-resolved Imaging (EPTI), which not only solves the long-standing problem of image distortion and blurring in conventional EPI acquisition, but also provides high imaging efficiency and resolves hundreds of multi-contrast images at sub-millisecond time interval across the readout. Dr. Wang has also developed other advanced acquisition and reconstruction methods for improved brain imaging, including 1) 3D-EPTI for ultra-fast quantitative multi-parametric MRI (3-minute 1-mm isotropic resolution whole brain T1, T2, T2* mapping), 2) fMRI with high microvascular/neuronal specificity to study cortical-depth dependent brain activities at ultra-high field, 3) high-resolution motion-robust in-vivo diffusion imaging.
Education
PhD, Harvard-MIT Health Sciences and Technology, Massachusetts Institute of Technology (MIT)
Select Publications
1. Wang F, Dong Z, Reese TG, Bilgic B, Katherine Manhard M, Chen J, Polimeni JR, Wald LL, Setsompop K. Echo planar time-resolved imaging (EPTI). Magn Reson Med. 2019 Jun;81(6):3599-3615. doi: 10.1002/mrm.27673. Epub 2019 Feb 3. PMID: 30714198; PMCID: PMC6435385.
2. Wang F, Dong Z, Wald LL, Polimeni JR, Setsompop K. Simultaneous pure T2 and varying T2′-weighted BOLD fMRI using Echo Planar Time-resolved Imaging for mapping cortical-depth dependent responses. Neuroimage. 2021 Oct 13;245:118641. doi: 10.1016/j.neuroimage.2021.118641. Epub ahead of print. PMID: 34655771.
3. Wang F, Dong Z, Tian Q, Liao C, Fan Q, Hoge WS, Keil B, Polimeni JR, Wald LL, Huang SY, Setsompop K. In vivo human whole-brain Connectom diffusion MRI dataset at 760 µm isotropic resolution. Sci Data. 2021 Apr 29;8(1):122. doi: 10.1038/s41597-021-00904-z. PMID: 33927203; PMCID: PMC8084962.
Highlights
ISMRM I.I. Rabi Young Investigator Award Finalist (2019 for EPTI)
United States Patent #11,022,665: Method for echo planar time-resolved magnetic resonance imaging (US20190369185A1)
United States Patent #10,871,534: Accelerated magnetic resonance imaging using a tilted reconstruction kernel in phase encoded and point spread function encoded K-space (US20190369186A1)