Dr. Hakan Ay is an MD with residency training in Neurology and fellowship training in Vascular Neurology. He currently serves as an Associate Professor at Harvard Medical School with appointments in both departments of Neurology and Radiology at the Massachusetts General Hospital. Dr. Ay has 28 y...
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Mesoscale Brain Mapping: Bridging Scales and Modalities in Neuroimaging
Recent advances both in the MGH Martinos Center for Biomedical Imaging and elsewhere are driving the convergence of microscopic- and macroscopic-scale study of the brain for human translational neuroscience, by developing and applying tools to study the spatial distribution and temporal orchestra...
Daphne Holt Receives MGH Research Scholars Award
The Martinos Center's Daphne Holt is among the distinguished investigators in the 2018 Class of MGH Research Scholars. She received the honor for her project "Altered neural mechanisms of personal space in schizophrenia: a novel biomarker of negative symptoms and treatment target." Schizophren...
Student FAQ
What type of students work at the Martinos Center? The Martinos Center is home to full-time Ph.D. and Master's students from various backgrounds, ranging from Physics, Chemistry, Computer Science and Engineering to Biology, Neuroscience and Psychology. The breadth of research at the Center provi...
Matt Rosen and Colleagues’ Journey Through the Secret Life of Plants
In the waning months of 1979, the legendary Motown artist Stevie Wonder released an album called Stevie Wonder’s Journey Through "The Secret Life of Plants," the soundtrack to the documentary film The Secret Life of Plants. Equal parts frustrating and strangely compelling, and notably using some ...
White Matter Changes Could Predict Cognitive Decline in Alzheimer’s Disease
Alzheimer’s disease is diagnosed based on abnormal pathology of two proteins in the brain: amyloid and tau. Research suggests, however, that other factors may also play a role. In a paper published online this week in the journal Neurology, a team of investigators at the Athinoula A. Martinos Cen...
‘It’s All in the Eyes’: The role of the amygdala in the experience and perception of fear
Researchers have long believed that the amygdala, an almond-shaped structure in the brain, is central to the experience and perception of fear. Studies initiated in the 1990s of a patient with a rare condition affecting the amygdala initially seemed to support this conclusion. However, as the MGH...
Artificial Intelligence Improves Treatment Monitoring in Patients with Glioma
This year, some 78,000 primary brain and other central nervous system (CNS) cancers will be diagnosed in the US alone. Researchers are actively developing new therapies for glioma, the most common type of primary brain tumor, but challenges remain in assessing whether patients are responding to t...
Tweets From the Front Lines
In the past few weeks, we've seen a shift in the Martinos Center's Twitter feed. Usually teeming with tweets about the latest research, upcoming conferences and occasionally the antics of someone's adorable dog, the feed is now, unsurprisingly, dominated by updates about COVID-19 and the medical ...
Mainak Jas
Dr. Jas completed his PhD from Telecom ParisTech. His thesis focused on automating MEG/EEG analysis pipelines. He is a proponent of open and reproducible science. He has been a key contributor to several open source neuroimaging tools: most notably MNE-Python, MNE-BIDS, and HNN-core. He develope...
A&E Series Highlights Imaging Study of Dissociative Identity Disorder Patient
The Martinos Center’s Robert Savoy is slated to appear in the final episode of the 6-part A&E series “The Many Sides of Jane” airing on the network tonight (Tuesday, February 19). The series follows Jane Hart, a 28-year-old mother of two with Dissociative Identity Disorder (DID, formerly c...
Deep Learning Algorithm Can Measure Disease Severity and Change on a Continuous Spectrum
Clinicians often use imaging to evaluate both the severity and progression of disease, in many cases by assigning severity to one of several categories based on the imaging findings and seeing whether and how the classification changes on follow-up. This approach can have its limits, though. B...
Ultrahigh-field MRI Tracks Development of Cortical Lesions in Multiple Sclerosis Patients
The development of lesions in the brain’s cortical gray matter is a strong predictor of neurological disability for people with multiple sclerosis (MS), according to a study reported today in the journal Radiology. The findings suggest a role for ultrahigh-field MRI in monitoring the progression ...
The Radiochemistry Team, and Everything That Doesn’t Go Wrong
PET-MR, a multimodality imaging technique that pairs the whole-body functional imaging of positron emission tomography (PET) with the local anatomic detail and morphological information of magnetic resonance (MR) imaging, shows great potential for clinical application. We still don’t know exactly...
Nutrition and Brain Growth in the Developing World
The aging pickup truck bounces along a dirt road somewhere outside Bissora, one of the larger towns in the Oio region of the West African nation of Guinea-Bissau. The road, a major thoroughfare in the region, is pocked with holes. The rest of the year these would be deep and dusty. But it’s July ...
The Secret Lives of Martinos Folk: Fighting Stereotypes of Women in Islam, One Karate Kick at a Time
Zeynab Alshelh has practiced karate since she was a young child growing up in Australia. For much of the time she has been involved with the sport, she has focused her efforts on the discipline known as shadow fighting, or Kata. Kata comprises a pre-arranged pattern of movements—kicks and punches...
Woman of the Year: Alexandra Touroutoglou
The Martinos Center’s Alexandra Touroutoglou has been named Woman of the Year in the “Expatriate” category by the Greek magazine Beauté. She accepted the award during a ceremony at the Athens Concert Hall, which was broadcast on March 8th in recognition of International Women’s Day. The award ...
Symposium to Explore ‘Mesoscale’ Imaging of the Human Brain
Registration is open for “Mesoscale Brain Mapping: Bridging Scales and Modalities in Neuroimaging,” a one-day symposium bringing together researchers using a range of imaging techniques to study brain function at the intersection of the micro- and macro- scales. The in-person event will be he...
The Year in Review: 2019
The MGH Martinos Center closed out the decade with yet another stellar year. In 2019, Center investigators reported advances in a range of areas – from technology development to basic science research and a host of clinical applications – and generally showed surprising / not-in-the-least-bit-su...
The Secret Lives of Martinos Folk: It’s Gonna Be a Lot Less Spooky Around Here
If you were in Building 149 of the Martinos Center on any given Halloween in the past decade, you might have come across a possibly startling scene: a nine-foot, anthropomorphic volcano wandering the halls; a moth-man with large, glowing eyes posing for photos; or maybe just a huge globule of glu...