Nanodiamonds – synthetic industrial diamonds only a few nanometers in size – have recently attracted considerable attention because of the potential they offer for the targeted delivery of vaccines and cancer drugs as well as for other uses. Thus far, options for imaging nanodiamonds have been li...
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New Software Improves Ability to Determine the Cause of Stroke
Determining the cause of an ischemic stroke is critical to preventing a second one and is a primary focus in the evaluation of stroke patients. But for all the importance of identifying the cause, physicians have long lacked a robust and objective means to do so. Now a team of investigators at...
With New PET Probe, Researchers Image Fibrosis of the Lungs
The MGH Martinos Center's Pauline Désogère and colleagues have described a new positron emission tomography (PET) probe that can help to advance noninvasive diagnosis of pulmonary fibrosis. Reported in a Science Translational Medicine paper published online today, the probe enables detection and ...
Robert Savoy
Dr. Savoy received his academic training in applied mathematics at MIT (BS 1971; MS 1975) and experimental psychology at Harvard University (PhD 1980). This period included 10 years of work at Polaroid Corporation’s Vision Research Laboratory, after which he joined the newly formed Rowland Instit...
Jason Stockmann
Jason Stockmann, PhD, is broadly interested in magnetic resonance imaging hardware and acquisition methods for improving data quality for both structural and functional imaging. He has worked on diverse MRI scanners ranging in field strength by two orders of magnitude, from low-field (80 mT) to u...
Advanced MRI of Spinal Cord Function Could Provide Important Information for the Treatment of Multiple Sclerosis
A team of investigators at the MGH Martinos Center for Biomedical Imaging and Vanderbilt University Medical Center has reported a new approach to measuring spinal cord function that could help in more accurately understanding the degree of spinal cord damage in relapsing-remitting multiple sclero...
Estimating Tumor Boundaries in Cancer Surgery With Fluorescence Lifetime Imaging
Cancer is the second leading cause of death in the United States, with an estimated 1,762,450 new cases diagnosed and 606,880 deaths in 2019 alone. While important advances have been made in the development of treatments for cancer, including surgery, a number of challenges remain. Not least: sur...
Deep Learning Offers Quantitative Means of Monitoring Disease Progression in Retinopathy of Prematurity
Retinopathy of prematurity (ROP) is an eye disorder affecting roughly two-thirds of premature infants weighing less than 250 g at birth and one of the leading causes of childhood blindness worldwide. Historically, clinical diagnosis of ROP has been subjective, resulting in considerable variabilit...
Publications Updates
May 11, 2020 The presubiculum links incipient amyloid and tau pathology to memory function in older persons Jacobs HIL, Augustinack JC, Schultz AP, Hanseeuw BJ, Locascio J, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. Neurology. 2020 May 5;94(18):e1916-e1928. doi: 10.1212/WNL.00...
Meher Juttukonda
Dr. Juttukonda’s research interests are in studying the balance between hemodynamic and metabolic function in the human brain as well as in the translation of these methods for characterizing microvascular health in cerebrovascular diseases. A principal objective of his work has been to develop q...
White Matter Changes Could Predict Cognitive Decline in Alzheimer’s Disease
Alzheimer’s disease is diagnosed based on abnormal pathology of two proteins in the brain: amyloid and tau. Research suggests, however, that other factors may also play a role. In a paper published online this week in the journal Neurology, a team of investigators at the Athinoula A. Martinos Cen...
Susie Huang Receives Jim Thrall, MD, Mentoring Award
The Martinos Center's Susie Huang, MD, PhD, was one of two research faculty in the Department of Radiology at Massachusetts Hospital to receive the 2024 Jim Thrall, MD, Mentoring Award. The award was established to recognize and honor mentoring contributions of faculty who have demonstrated susta...
Ilknur Ay
Dr. Ay is an Assistant Professor at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital and Harvard Medical School. She has a broad background in vascular pharmacology with fellowship training in neuroscience at the Massachusetts General Hospital. Dr. Ay’s main researc...
Mathias Davids
Mathias Davids, PhD, is currently an Instructor in Radiology at Harvard Medical School. He received a BSc in Biomedical Engineering at University of Luebeck in 2011, and an MSc and Ph.D. in Biomedical Physics at Heidelberg University in 2014 and 2018, respectively. Dr. Davids has a strong backgro...
The (Totally True) Legend of Thomas Witzel and the Ultrahigh-field MRI Quench
Sometimes we get the hero we need. In the summer of 2017, the 7T MRI scanner at the MGH Martinos Center suffered a quench: a sudden loss of superconductivity resulting in a complete loss of the scanner’s magnetic field. In short, it broke. Without a magnetic field, the instrument was inoperabl...
MGB Radiology Research Celebration 2023
In 2023, the joint departments of Radiology Research at Massachusetts General Hospital and Brigham and Women's Hospital seek to recognize and support the accomplishments of our outstanding research faculty. We are immensely appreciative of the quality and quantity of their work. The annual Rad...
‘It’s All in the Eyes’: The role of the amygdala in the experience and perception of fear
Researchers have long believed that the amygdala, an almond-shaped structure in the brain, is central to the experience and perception of fear. Studies initiated in the 1990s of a patient with a rare condition affecting the amygdala initially seemed to support this conclusion. However, as the MGH...
Lisa Feldman Barrett
Lisa Feldman Barrett, PhD, is University Distinguished Professor of Psychology and Director of the Interdisciplinary Affective Science Laboratory (IASLab) at Northeastern University. She also holds research appointments in the Psychiatric Neuroimaging Program in the Department of Psychiatry and a...
Early Screening of ASD With a New Eye-tracking Paradigm
Studies have shown that early diagnosis and intervention significantly impact the prognosis of individuals with autism spectrum disorder (ASD): the earlier the detection and diagnosis, the better the prognosis and functional status later in life. Currently, the average age of diagnosis is approxi...
‘Women in Science’ Series Tackles Sexism, Other Issues
The MGH Martinos Center’s first-ever “Women in Science” seminar series, held this spring, brought together investigators, staff and others from throughout the community for a host of important and thought-provoking discussions. The series proved so successful the organizers are planning to hold a...