Chronic liver disease is a growing health concern in the U.S. and around the world, with links to alcoholism, diabetes and even obesity. One of the early manifestations of the disease is fibrosis, an excessive buildup of scar tissue that results from repeated injury to the liver. While its effect...
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Publications Updates
May 11, 2020 The presubiculum links incipient amyloid and tau pathology to memory function in older persons Jacobs HIL, Augustinack JC, Schultz AP, Hanseeuw BJ, Locascio J, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. Neurology. 2020 May 5;94(18):e1916-e1928. doi: 10.1212/WNL.00...
The Year in Review: 2019
The MGH Martinos Center closed out the decade with yet another stellar year. In 2019, Center investigators reported advances in a range of areas – from technology development to basic science research and a host of clinical applications – and generally showed surprising / not-in-the-least-bit-su...
Christian Farrar
The Farrar group's research program is focused on the development of novel Magnetic Resonance molecular imaging contrast agents and methods and on the development of innovative Magnetic Resonance Imaging (MRI) methods for characterizing vascular structure and function. The tools being developed i...
Jayashree Kalpathy-Cramer
Dr. Kalpathy-Cramer is an Associate Professor of Radiology at Harvard Medical School, Co-Director of the QTIM lab and the Center for Machine Learning at the Athinoula A. Martinos Center and Scientific Director at the MGH & BWH Center for Clinical Data Science. Her research areas include machi...
New Software Concept Promises Boost for Clinical Trial Recruitment
What if you held a clinical trial and nobody came? While plenty of patients are eager to participate, researchers often have difficulty reaching their target enrollments for clinical trials, the goal of which is to determine the safety and efficacy of new drugs or therapies before they are bro...
Optical Imaging
The Martinos Optics Research facilities consists of multiple separate lab facilities including 1) fiber optic and electronics fabrication and testing, 2) instrumentation system development and testing, 3) small animal studies, 4) optical physics labs with floating tables, and 5) human subject tes...
Eric Gale
Dr. Gale applies chemistry to solve unmet challenges in radiology and biomedical imaging. A major area of current focus is developing magnetic resonance imaging probes to non-invasively map and quantify pathologic change at the molecular level. His group is capitalizing on the transition metal p...
The Road to MPI
Functional MRI has proved a transformative technology, yielding previously unimaginable insights into the workings of the brain. But what if there were another approach, one with dramatically higher sensitivity, that could shed even more light on these mysteries? What might we learn then? Larry ...
Novel PET Radiotracer Offers Possible ‘Smell Test’ for Dementia
Olfactory health – how well we are able to smell – is a reliable marker of the health of the brain, but the “smell identification tests” commonly used in studies of olfactory health do not offer a complete picture of what is happening. Now, using a novel PET radiotracer called Neuroflux, a team o...
Mesoscale Brain Mapping: Bridging Scales and Modalities in Neuroimaging
Recent advances both in the MGH Martinos Center for Biomedical Imaging and elsewhere are driving the convergence of microscopic- and macroscopic-scale study of the brain for human translational neuroscience, by developing and applying tools to study the spatial distribution and temporal orchestra...
Peter Caravan
Peter Caravan, PhD, is co-director of the Institute for Innovation in Imaging (I3) at Massachusetts General Hospital and a Professor of Radiology at Harvard Medical School. He leads a multidisciplinary and translational molecular imaging lab (the Caravan Lab) focused on the invention of novel mol...
Christopher Bridge
Dr Bridge is trained as an engineer, with MEng (Distinction) and DPhil degrees from the University of Cambridge and University of Oxford, respectively. He has worked in the area of medical image analysis for nearly a decade. His work on his doctoral thesis involved the development of a system for...
Steven Stufflebeam
Steven Stufflebeam, MD, translates basic science and advanced imaging technology into everyday clinical practice. His laboratory aims to improve the health care for patients with epilepsy, schizophrenia, brain tumors and hearing impairments. His training is in biomedical engineering, mathematics ...
Kenneth Kwong
Kenneth Kwong, PhD, has been conducting magnetic resonance imaging (MRI) research for more than 30 years with expertise in diffusion (R.1), functional imaging (R.2) and perfusion imaging (R.3). He was one of the earliest researchers to explore MR diffusion imaging of healthy subjects and patients...
Eva-Maria Ratai
Dr. Eva-Maria Ratai has been Director of Clinical Magnetic Resonance Spectroscopy at Massachusetts General Hospital (MGH) since 2003. After completing her doctoral thesis in physical chemistry at the University of Münster in Germany in 2000, and her first post-doctoral position in the Department ...
Chongzhao Ran
Chongzhao Ran, PhD, is an Associate Professor in Radiology at Massachusetts General Hospital and Harvard Medical School. He received a Master's degree in medicinal chemistry from China Pharmaceutical University and a PhD in medicinal chemistry from Shanghai Institute of Pharmaceutical Industry, C...
Ciprian Catana
Dr. Catana is director of Integrated MR-PET Imaging at the MGH Martinos Center for Biomedical Imaging and a Professor in Radiology at Harvard Medical School. He has extensive experience in combining PET and MRI and is currently focusing on developing quantitative MR-PET for human use. Working clo...
Hamid Sabet
Hamid Sabet, is Assistant Professor of Radiology at Harvard Medical School and a Cyclotron/Medical Physicist at the Division of Nuclear Medicine and Molecular Imaging, Radiology Department, Massachusetts General Hospital. He is the director of Radiation Physics and Instrumentation Lab at the Mart...
Iris Yuwen Zhou
Dr. Iris Yuwen Zhou is an Assistant Professor of Radiology at Massachusetts General Hospital and Harvard Medical School and a faculty member in the Athinoula A. Martinos Center for Biomedical Imaging. She has a background in both electronic engineering and biomedical engineering, with specific tr...